Apoptosis Inductionof Armeniacae Semen Extractin Human Acute Leukemia (NALM-6 and KG-1) Cells
نویسندگان
چکیده
منابع مشابه
The Effect of Gaillardin on Proliferation and Apoptosis of Acute Lymphoblastic Leukemia Cell Line (Nalm-6)
Background: Due to increased cancer chemotherapy resistance, the use of natural compounds in cancer treatment has been considered in recent years. Inula-Oculus-Christi, is one of the high importance plants in the field of traditional medicine. It has been shown that extract of this plant has cytotoxic effects on breast cancer cells. Objective: Therefore, the aim of this study was to evaluate t...
متن کاملThe effect of Ganoderic Acid A on miR-17-5p and miR-181b expression level and apoptosis induction in human leukemia Nalm-6 cells
Background: In various cancers, Ganoderic Acid A (GAA), an active triterpenoid derived from Ganoderma lucidum, has been proved to show potent anti-tumor effects. However, the possible impacts of GAA on the human leukemia cell line (Nalm-6) are not fully elucidated. Therefore, this research aimed to study the antineoplastic effect of GAA on Nalm-6 cells. Materials and Methods: In this laborator...
متن کاملCurcumol induced apoptosis of human acute myeloid leukemia KG-1a cells
Objective: To investigate the effect of curcumol on the apoptosis of human acute myeloid leukemia KG-1a cells and to explore possible mechanism of action. Methods: CCK-8 method was used to detect the cell viability of KG-1a cells treated by 10, 20, 40, 60, 80 uM curcumol, and that of KG-1a cells treated by 40 uM curcumol after different periods of time. Confocal microscopy was used to observe m...
متن کاملاثر سینرژیستی ایندول تری کربینول با دوکسوروبیسین در افزایش القای آپوپتوز بر رده سلولی لوسمی لنفوبلاستیک حاد (NALM-6)
Background and Aim: Indole-3-carbinol (I3C), found in Brassica species vegetables, exhibits antitumor effects. It has been shown that I3C induces apoptosis in various cell types through inactivation of the nuclear factor-kappa B (NF- k B) pathway. Anthracyclines such as doxorubicin, is widely used in the treatment of hematological malignancies, induce apoptosis in tumor cells via DNA damage and...
متن کاملInvestigating the apoptotic and anti-proliferative effects of Juniperus excelsa fractions on Acute Lymphoblastic leukemia cell line (Nalm-6)
Abstract Background and Objectives Acute lymphoblastic leukemia is a hematological malignancy of lymphoid lineage. Side effects of chemotherapy drugs is a major reason for the tendency to use Herbal medicines. Previous studies on Juniperus excelsa (J.excelsa) have shown anti-cancer properties on some cancer cell lines. This study aimed to investigate the effect of three fractions of J.excelsa ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Hematology-Oncology and Stem Cell Research
سال: 2019
ISSN: 2008-2207
DOI: 10.18502/ijhoscr.v13i3.1269